Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | PDE2A | O00408 | 5/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 6/20 | 0.48 |
| ▸ | CD99 | P14209 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.47 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758245 | 0.85 | ADORA3 (0.54) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4758281 | 0.84 | ADORA3 (0.56) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4758255 | 0.83 | ADORA3 (0.56) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4757814 | 0.83 | ADORA3 (0.56) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL6874040 | 0.81 | HINT1 (0.54) | PDE3ANT5E | |
| SCHEMBL6875278 | 0.79 | HINT1 (0.39) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL14252588 | 0.79 | ADORA3 (0.74) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL14252597 | 0.77 | ADORA3 (0.50) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL19470036 | 0.76 | DNMT1 (0.48) | ADORA3P2RY11ALDH1A1LMNATP53 | |
| SCHEMBL3437027 | 0.75 | ADORA3 (0.72) | ADORA3CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342003-B2 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342003-B2 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| US-20060135466-A1 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. | 2006-06-22 | — | — | US | disclosed |
| WO-2005033121-A2 | SYNTHESIS OF 2-ARALKYLOXYADENOSINES, 2-ALKOXYADENOSINES, AND THEIR ANALOGS | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135466-A1 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | ADA, ADAR, DCTD | ADORA3 44/4885CA1 3973/4885CA2 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.