Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263309 | 0.88 | TRPV1 (0.53) | TRPV1TRPV4KMT2AKCNQ3KCNQ2 | |
| SCHEMBL14083706 | 0.87 | TRPV1 (0.54) | TRPV1KMT2AMEN1KCNQ3KCNQ2 | |
| SCHEMBL14083707 | 0.87 | TRPV1 (0.56) | TRPV1KMT2AMEN1KCNQ3KCNQ2 | |
| SCHEMBL14083635 | 0.87 | TRPV1 (0.56) | TRPV1KMT2AMEN1KCNQ3KCNQ2 | |
| SCHEMBL14083633 | 0.86 | TRPV1 (0.54) | TRPV1ALDH1A1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL14252870 | 0.85 | TRPV4 (0.59) | TRPV4KMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL14083652 | 0.85 | TRPV1 (0.57) | TRPV1TRPV4KCNQ3KCNQ2KCNE1 | |
| SCHEMBL14083676 | 0.85 | TRPV1 (0.56) | TRPV1KMT2AMEN1KCNQ3KCNQ2 | |
| SCHEMBL14083648 | 0.84 | TRPV1 (0.71) | TRPV1MAPT | |
| SCHEMBL14083634 | 0.84 | RAB9A (0.53) | TRPV1KMT2AMEN1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |