Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PLK1 | P53350 | 10/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14082419 | 0.86 | NPC1 (0.61) | ALDH1A1MAPTATMKDM1AHDAC1 | |
| SCHEMBL29179747 | 0.83 | MEN1 (0.82) | MEN1KMT2AGFERALDH1A1MAPT | |
| SCHEMBL14075221 | 0.82 | MEN1 (0.72) | MEN1KMT2AGFERALDH1A1MAPT | |
| SCHEMBL11834604 | 0.81 | MEN1 (0.85) | MEN1KMT2AGFERALDH1A1MAPT | |
| SCHEMBL14082325 | 0.80 | NPC1 (0.60) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14082429 | 0.80 | RXFP1 (0.60) | MEN1KMT2AALDH1A1MAPTSERPINE1 | |
| SCHEMBL14082359 | 0.79 | NPC1 (0.71) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL14082392 | 0.79 | KCNMA1 (0.56) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL19433797 | 0.78 | LOXL2 (0.60) | ALDH1A1HTTKDM1AHDAC1HDAC6 | |
| SCHEMBL14082399 | 0.78 | NPC1 (0.63) | MEN1KMT2AALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |