Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771226 | 0.87 | PRKCA (0.66) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL772828 | 0.85 | PRKCA (0.64) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL30486080 | 0.85 | PRKCA (0.64) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL877519 | 0.84 | PRKCA (0.63) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3079634 | 0.83 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3080762 | 0.83 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL4830083 | 0.82 | PRKCA (0.51) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3096348 | 0.82 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL2957529 | 0.82 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL394639 | 0.80 | PRKCA (0.63) | PRKCAMMP12NR1I2SCN9AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348425-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-03-25 | — | — | US | disclosed |
| US-7348425-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-03-25 | — | — | US | disclosed |
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |