Harpagide

Harpagide

SCHEMBL1425414

C[C@]1(O)C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]21

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.61
▸ TSHR P16473 1/20 0.61
▸ KDM4E B2RXH2 1/20 0.46
▸ GLA P06280 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ POLB P06746 1/20 0.41
▸ CTDSP1 Q9GZU7 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ SYNJ2 O15056 2/20 0.40
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ HSP90AA1 P07900 2/20 0.39
▸ MAPT P10636 2/20 0.37
▸ PTPN1 P18031 2/20 0.37
▸ STAT3 P40763 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Harpagide SCHEMBL30132931 1.00 ALDH1A1 (0.61) ALDH1A1TSHRKDM4EGLACYP3A4
Harpagide SCHEMBL29385820 1.00 ALDH1A1 (0.61) ALDH1A1TSHRKDM4EGLACYP3A4
SCHEMBL29727271 0.84 ALDH1A1 (0.71) ALDH1A1TSHRKDM4EGLACYP3A4
SCHEMBL29208523 0.84 ALDH1A1 (0.71) ALDH1A1TSHRKDM4EGLACYP3A4
SCHEMBL29425887 0.84 ALDH1A1 (0.71) ALDH1A1TSHRKDM4EGLACYP3A4
SCHEMBL29425781 0.83 ALDH1A1 (0.49) ALDH1A1TSHRKDM4EGLACYP3A4
SCHEMBL422972 0.81 ALDH1A1 (0.53) ALDH1A1TSHRKDM4EGLACYP3A4
SCHEMBL9057878 0.80 ALDH1A1 (0.51) ALDH1A1TSHRKDM4EGLACYP3A4
Antirrhinoside SCHEMBL1424987 0.79 ALDH1A1 (0.51) ALDH1A1TSHRKDM4EGLACYP3A4
Antirrhinoside SCHEMBL27233579 0.79 ALDH1A1 (0.51) ALDH1A1TSHRKDM4EGLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 — — EP claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 — — EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP claimed
EP-4379068-B1 IRIDOID OR SECO-IRIDOID DERIVATIVES AND THEIR USE IN A TANNING PROCESS INSTITUT NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) 2025-06-04 — — EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO claimed
US-20240343784-A1 TREATMENT OF MEDICATION OVERUSE HEADACHE USING ANTI-CGRP OR ANTI-CGRP-R ANTIBODIES H LUNDBECK AS (DK) 2024-10-17 — — US claimed
EP-4379068-A1 IRIDOID OR SECO-IRIDOID DERIVATIVES AND THEIR USE IN A TANNING PROCESS Institut National Des Sciences Appliquées De Rouen (FR) 2024-06-05 — — EP claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO claimed
US-20230346970-A1 CENTRAL NERVOUS SYSTEM DELIVERY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS AND PSILOCYBIN SILO PHARMA, INC. 2023-11-02 — — US claimed
US-20230248838-A1 CENTRAL NERVOUS SYSTEM DELIVERY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS SILO PHARMA, INC. 2023-08-10 — — US claimed
US-7060693-B1 Ajuga turkestanica extract and its cosmetic uses LVMH RECHERCHE (FR) 2006-06-13 — — US claimed
WO-2006017341-A2 COATED VAGINAL DEVICES FOR VAGINAL DELIVERY OF THERAPEUTICALLY EFFECTIVE AND/ OR HEALTH-PROMOTING AGENTS UMD, INC. (US) 2006-02-16 — — WO claimed
US-20050276836-A1 Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents UMD, INC. 2005-12-15 — — US claimed
EP-1231893-B1 AJUGA TURKESTANICA EXTRACT AND ITS COSMETIC USES LVMH RECH (FR) 2004-08-18 — — EP claimed
US-6531582-B1 Medicinal plants; herbs; plant extracts; Cibotii rhizoma; use therapy for arthritis, osteoporosis, ruptured disc Shin, Joon Shik (KR) 2003-03-11 — — US claimed
WO-2001001996-A9 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIV WESTERN AUSTRALIA (AU) 2002-09-12 — — WO claimed
WO-2001001996-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIVERSITY OF WESTERN AUSTRALIA (AU) 2001-01-11 — — WO claimed
US-5929038-A ADMINISTERING IRIDOID COMPOUNDS CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) 1999-07-27 — — US claimed
US-5589182-A AQUEOUS EXTRACTS OF TISSUE OF SPECIFIC CHINESE PLANTS AND HERBS TASHIRO RENKI (JP) 1996-12-31 — — US claimed
CN-1082895-A The Pharmaceutical composition that treatment hepatitis B virus (HBV) infects CHOONGWAE PHARMA CO LTD (KR) 1994-03-02 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346970-A1 CENTRAL NERVOUS SYSTEM DELIVERY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS AND PSILOCYBIN CNR2, NPSR1, CNR1 ALDH1A1 3677/4885TSHR 4498/4885KDM4E 4639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback