Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582580 | 0.88 | CTSS (0.48) | CTSSCTSKTACR3S1PR3KLK5 | |
| SCHEMBL1554126 | 0.88 | CTSS (0.48) | CTSSCTSKTACR3S1PR3KLK5 | |
| SCHEMBL1554122 | 0.88 | CTSS (0.48) | CTSSCTSKTACR3S1PR3KLK5 | |
| SCHEMBL16174090 | 0.88 | CTSK (0.50) | CTSSCTSKPPARGPPARAS1PR3 | |
| SCHEMBL16171653 | 0.88 | CTSK (0.50) | CTSSCTSKPPARGPPARAS1PR3 | |
| SCHEMBL3503830 | 0.87 | CTSS (0.47) | CTSSCTSKS1PR3MAPTALDH1A1 | |
| SCHEMBL1525552 | 0.87 | S1PR3 (0.52) | CTSSCTSKPPARGPPARATACR3 | |
| SCHEMBL21787638 | 0.87 | CTSS (0.47) | CTSSCTSKS1PR3KLK5PDE2A | |
| SCHEMBL2426585 | 0.87 | NPSR1 (0.50) | CTSSCTSKPPARGPPARATACR3 | |
| SCHEMBL13808330 | 0.87 | NPSR1 (0.50) | CTSSCTSKPPARGPPARATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1894911-A1 | VITAMIN D-LIKE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-03-05 | — | — | EP | disclosed |