SCHEMBL1425534

SCHEMBL1425534

Cc1sccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Boric Acid SCHEMBL6813589 0.90 POLB (0.35)
SCHEMBL13990519 0.70 POLB (0.32)
SCHEMBL770898 0.69 POLB (0.44)
SCHEMBL16887409 0.69 PLA2G10 (0.40)
SCHEMBL113923 0.69
SCHEMBL134132 0.69
SCHEMBL7921236 0.69 CYP2A6 (0.47)
SCHEMBL7388070 0.66 PTGS2 (0.46)
SCHEMBL14972723 0.65
SCHEMBL9778552 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964666-A Continuous flow synthesis method of zirconocene type olefin polymerization catalyst 吉林大学 2024-05-03 CN claimed
CN-115650951-B Diaryl ethylene organic photochromic material and preparation method thereof 中国人民解放军96901部队25分队 2023-12-26 CN claimed
CN-115650951-A Diaryl ethylene organic photochromic material and preparation method thereof 中国人民解放军96901部队25分队 2023-01-31 CN claimed
CN-114507305-A Method for synthesizing zirconocene type olefin polymerization catalyst 吉林大学 2022-05-17 CN claimed
CN-110117270-A A kind of 3-(thiophene -2- base) cyclohexanone framework compound preparation method 山西大学 2019-08-13 CN claimed
EP-4695242-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
CN-119698414-A Indole-phenyl piperidine compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2025-03-25 CN disclosed
WO-2025044926-A1 THIENYLSULFONYL CARBAMATES AS AT2R AGONISTS 武汉人福创新药物研发中心有限公司 2025-03-06 WO disclosed
CN-119504723-A Thiophene sulfonyl carbamates as AT2R agonists 武汉人福创新药物研发中心有限公司 2025-02-25 CN disclosed
WO-2024212024-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF META PHARMACEUTICALS (HK) LIMITED (CN) 2024-10-17 WO disclosed
WO-2024212907-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF META PHARMACEUTICALS (HK) LIMITED (CN) 2024-10-17 WO disclosed
CN-115667269-B Pyridone condensed ring derivative-containing inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2024-09-17 CN disclosed
EP-0382106-B1 Process for manufacturing thiophene derivatives HOECHST AG (DE) 1995-06-07 EP disclosed
US-5100520-A Electrochemical Dehalogenation HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
US-4992534-A Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-12 US disclosed
EP-0382106-A2 Process for manufacturing thiophene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-16 EP disclosed
EP-0303269-A2 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-02-15 EP disclosed
EP-0043486-A2 Flavouring agent for animal food HAARMANN & REIMER GMBH (DE) 1982-01-13 EP disclosed
EP-0000633-B1 PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED-THIEN-3-YLACETIC ACID AND DERIVATIVES THEREOF BEECHAM GROUP PLC (GB) 1981-11-04 EP disclosed
US-4005095-A PERIPHERAL-CORONARY-CEREBRAL VASODILATORS, DECONGESTANTS, SPASMOLYTIC AND PAPAVERINE-LIKE ACTIVITY INNOTHERA (FR) 1977-01-25 US disclosed