SCHEMBL770898

SCHEMBL770898

Brc1ccsc1-c1sccc1Br

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.44
CASP3 P42574 1/20 0.40
CES1 P23141 1/20 0.39
MAPT P10636 3/20 0.38
RXFP1 Q9HBX9 2/20 0.38
NPC1 O15118 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYP2A6 P11509 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
ADRA1D P25100 3/20 0.32
PTPRC P08575 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16593598 0.87 POLB (0.38) POLBCASP3CES1MAPTRXFP1
SCHEMBL7921236 0.84 CYP2A6 (0.47) POLBCASP3MAPTRXFP1NPC1
SCHEMBL2195598 0.81 POLB (0.38) POLBCASP3CES1MAPTRXFP1
SCHEMBL29726734 0.81 POLB (0.35) POLBCASP3MAPTRXFP1NPC1
SCHEMBL519565 0.79 MAPK1 (0.44) POLBCASP3MAPTRXFP1CYP2A6
SCHEMBL18719440 0.79 CASP3 (0.38) POLBCASP3CES1MAPTRXFP1
SCHEMBL16546150 0.77 PTPRC (0.38) POLBCASP3CES1MAPTRXFP1
SCHEMBL5181264 0.76 MAPT (0.37) POLBCES1MAPTRXFP1NPC1
SCHEMBL9825770 0.75 POLB (0.42) POLBCASP3MAPTRXFP1NPC1
SCHEMBL22129703 0.75 ESR1 (0.43) POLBCASP3CES1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010996-A Preparation method and application of dual-response fluorescent probe for detecting polarity and peroxynitrite 郑州大学 2026-05-12 CN claimed
CN-119594840-A PVA-based oxygen-permeable and moisture-permeable strain sensor and preparation method thereof 北京印刷学院 2025-03-11 CN claimed
CN-118165646-B Asphalt anti-sticking release agent and preparation method thereof 长春市城建维护集团股份有限公司 2024-09-03 CN claimed
CN-118162110-A Preparation method of porous organic polymer material for adsorbing aflatoxin in vegetable oil and adsorption removal method 中国农业科学院油料作物研究所 2024-06-11 CN claimed
CN-118173857-A Lithium-halogen-based double-ion battery taking sulfur/halogenated thiophene composite material as positive electrode 齐齐哈尔大学 2024-06-11 CN claimed
CN-118165205-A Dithiophene-based triazine polymer and preparation method thereof 桂林理工大学 2024-06-11 CN claimed
CN-118165646-A Asphalt anti-sticking release agent and preparation method thereof 长春市城建维护集团股份有限公司 2024-06-11 CN claimed
CN-117736416-A Polymer donor material based on thiophene imide as construction unit and preparation method thereof 安徽师范大学 2024-03-22 CN claimed
CN-113429382-B 1,1' - ([ 2,2' -bithiophene ] -3,3' -diyl) bis (ethan-1-one) and preparation and application thereof 山西大同大学 2023-03-14 CN claimed
CN-110606858-B Preparation method of thiophene organic semiconductor material intermediate 上海博栋化学科技有限公司 2022-07-26 CN claimed
CN-111116607-A Hole transport material based on indeno [2,1-b ] carbazole and preparation method and application thereof 天津理工大学 2020-05-08 CN claimed
CN-108558912-B Preparation method of dithieno [3,2-b:2',3' -d ] selenophene 河南大学 2020-02-28 CN claimed
CN-110655641-A Method for preparing conductive polythiophene and conductive paper by atmospheric pressure plasma in-situ solid state polymerization 北京印刷学院 2020-01-07 CN claimed
CN-110606858-A Preparation method of thiophene organic semiconductor material intermediate 上海博栋化学科技有限公司 2019-12-24 CN claimed
EP-3278379-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES Sony Corporation (JP) 2018-02-07 EP claimed
US-20020077356-A1 Nonsteroidal antiinflammatory agents SCHERING AKTIENGESELLSCHAFT (DE) 2002-06-20 US claimed
EP-0918766-B1 SELF-ACID-DOPED HIGHLY CONDUCTING POLYTHIOPHENES UNIV MONTREAL (CA) 2002-02-06 EP claimed
US-6051679-A A META-ALKYLSULFONATE OR META-ALKYLSULFONIC ACID MONOMER CONTAINING POLYTHIOPHENE; POLYMERIZED BY OXIDATIVE DOPING OF THE MONOMER UNIVERSITEDE MONTREAL (CA) 2000-04-18 US claimed
EP-0918766-A1 NOVEL SELF-ACID-DOPED HIGHLY CONDUCTING POLYTHIOPHENES UNIVERSITE DE MONTREAL (CA) 1999-06-02 EP claimed
WO-1998003499-A1 NOVEL SELF-ACID-DOPED HIGHLY CONDUCTING POLYTHIOPHENES UNIVERSITE DE MONTREAL (CA) 1998-01-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077356-A1 Nonsteroidal antiinflammatory agents PTGS1, PTGES2, PTGES POLB 3512/4885CASP3 578/4885CES1 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.