Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GRM5 | P41594 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688782 | 0.72 | GRM5 (0.50) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| Quisqualate SCHEMBL3674132 | 0.72 | CYP1A2 (1.00) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| Quisqualate SCHEMBL136819 | 0.72 | CYP1A2 (1.00) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| SCHEMBL12648453 | 0.68 | GRM5 (0.54) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| SCHEMBL4825291 | 0.67 | KDM4E (0.35) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| Bromide SCHEMBL9206069 | 0.67 | GRM5 (0.53) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| SCHEMBL8545723 | 0.63 | FFAR1 (0.41) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| SCHEMBL20865055 | 0.62 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8550945 | 0.60 | FFAR1 (0.46) | ALDH1A1KDM4EGRM5MEN1KMT2A | |
| SCHEMBL8546551 | 0.60 | FFAR1 (0.46) | ALDH1A1KDM4EGRM5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345040-B2 | Reverse-turn mimetics and compositions and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2008-03-18 | — | — | US | disclosed |