Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | GRM5 | P41594 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | FOLH1 | Q04609 | 1/20 | 1.00 |
| ▸ | GRM1 | Q13255 | 1/20 | 1.00 |
| ▸ | GRM3 | Q14832 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 1.00 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.71 |
| ▸ | GRIA1 | P42261 | 9/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quisqualate SCHEMBL3674132 | 1.00 | CYP1A2 (1.00) | CYP1A2GRM5KDM4EBLMKMT2A | |
| Quisqualate SCHEMBL27790631 | 0.98 | CYP1A2 (0.97) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL31532299 | 0.83 | GRM5 (1.00) | CYP1A2GRM5KDM4EBLMKMT2A | |
| Quisqualate SCHEMBL7928396 | 0.80 | FOLH1 (0.64) | CYP1A2GRM5KDM4EBLMKMT2A | |
| Quisqualate SCHEMBL15528499 | 0.80 | CYP1A2 (0.64) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL26036945 | 0.74 | GRM5 (0.58) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL14255773 | 0.72 | ALDH1A1 (0.56) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL24115280 | 0.69 | GRM5 (0.53) | CYP1A2GRM5KDM4EBLMKMT2A | |
| Quisqualate SCHEMBL13319908 | 0.68 | KDM4E (0.51) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL31532300 | 0.67 | GRM5 (0.55) | CYP1A2GRM5KDM4EBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3688 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025199636-A1 | TARGETED RADIOLIGAND COMPOUNDS AND USES THEREOF | MCMASTER UNIVERSITY (CA) | 2025-10-02 | — | — | WO | claimed |
| US-20250213564-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. | 2025-07-03 | — | — | US | claimed |
| US-20250064948-A1 | GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING | THE JOHNS HOPKINS UNIVERSITY | 2025-02-27 | — | — | US | claimed |
| US-12156895-B2 | Composition, containing Quisqualis indica extract, for preventing or treating prostatic hyperplasia | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) | 2024-12-03 | — | — | US | claimed |
| US-12156879-B2 | Combining BACE1 inhibitors with mGluR agonists for Alzheimer's disease therapy | UNIVERSITY OF CONNECTICUT (US) | 2024-12-03 | — | — | US | claimed |
| EP-4436979-A1 | CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF | Full-Life Technologies HK Limited (HK) | 2024-10-02 | — | — | EP | claimed |
| US-11998017-B2 | Bio-pesticide for Japanese beetles | HABIB MATIAS (US) | 2024-06-04 | — | — | US | claimed |
| US-20230345948-A1 | Bio-pesticide for Japanese beetles | HABIB MATIAS (US) | 2023-11-02 | — | — | US | claimed |
| US-11771726-B2 | Composition, containing Quisqualis indica extract, for preventing or treating prostatic hyperplasia | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (KR) | 2023-10-03 | — | — | US | claimed |
| US-20230285322-A1 | Biomarkers for Efficacy of Prophylactic Treatments Against Stress-Induced Affective Disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-09-14 | — | — | US | claimed |
| WO-1992019717-A1 | A HIGH-AFFINITY HUMAN GLUTAMATE/ASPARTATE UPTAKE SYSTEM | BAYLOR COLLEGE OF MEDICINE (US) | 1992-11-12 | — | — | WO | claimed |
| WO-1992010583-A1 | G PROTEIN-COUPLED GLUTAMATE RECEPTORS | ZYMOGENETICS, INC. (US) | 1992-06-25 | — | — | WO | claimed |
| EP-0439544-A1 | IN VIVO NEUROTROPHIC CYTOPROTECTIVE ALCOHOLS. | UNIV CALIFORNIA (US) | 1991-08-07 | — | — | EP | claimed |
| US-5026704-A | Neuroleptic agent, quisqualate-antagonist | NOVO NORDISK A/S (DK) | 1991-06-25 | — | — | US | claimed |
| US-4948794-A | NEUROLEPTIC AGENTS | A/S FERROSAN (DK) | 1990-08-14 | — | — | US | claimed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | claimed |
| EP-0374534-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-06-27 | — | — | EP | claimed |
| WO-1990004388-A1 | IN VIVO NEUROTROPHIC CYTOPROTECTIVE ALCOHOLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-03 | — | — | WO | claimed |
| WO-1989007098-A1 | BUTYRL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 1989-08-10 | — | — | WO | claimed |
| EP-0315959-A2 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-05-17 | — | — | EP | claimed |