Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978083 | 0.89 | PARP10 (0.46) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL26405759 | 0.79 | F7 (0.40) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL14255904 | 0.79 | ALDH1A1 (0.47) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL14302646 | 0.77 | PARP10 (0.38) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL2294908 | 0.74 | BCHE (0.43) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL531817 | 0.74 | MAPT (0.54) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL5546719 | 0.71 | ALDH1A1 (0.58) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL20647077 | 0.71 | MAPT (0.50) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL3111834 | 0.71 | MAPT (0.50) | PARP10PARP1ALDH1A1MAPTGAA | |
| SCHEMBL30634161 | 0.71 | MAPT (0.50) | PARP10PARP1ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |