Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14255914 | 0.89 | PARP10 (0.40) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL5546719 | 0.78 | ALDH1A1 (0.58) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL18801014 | 0.74 | PARP10 (0.50) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL21160781 | 0.74 | PARP10 (0.42) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL22368737 | 0.73 | ALDH1A1 (0.42) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL11802702 | 0.72 | BRD4 (0.44) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL12461 | 0.72 | DRD2 (0.59) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL14255904 | 0.71 | ALDH1A1 (0.47) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL13950049 | 0.71 | PARP10 (0.47) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL22726443 | 0.71 | ALDH1A1 (0.39) | PARP10PARP1PARP11ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053240-A1 | PEPTIDOMIMETICS AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-03-22 | — | — | WO | disclosed |