Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624855 | 0.82 | SLC6A4 (0.66) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL795619 | 0.81 | SLC6A4 (0.63) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| Oxalic Acid SCHEMBL9595892 | 0.78 | SLC6A4 (0.56) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL8707560 | 0.76 | SLC6A2 (0.53) | HRH1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14704876 | 0.76 | SLC6A4 (0.56) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL25369234 | 0.76 | SLC6A2 (0.53) | HRH1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17633193 | 0.76 | SLC6A4 (0.56) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL24136460 | 0.76 | SLC6A4 (0.56) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL20086419 | 0.76 | SLC6A4 (0.56) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL8712781 | 0.76 | SLC6A2 (0.53) | HRH1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338965-B2 | 3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines | PHARMACIA & UPJOHN COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338965-B2 | 3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines | PHARMACIA & UPJOHN COMPANY (US) | 2008-03-04 | — | — | US | disclosed |