SCHEMBL14256372

SCHEMBL14256372

C[C@]12CCC(=O)C=C1C1CC1C1C2CC[C@@]2(C)C1C1CC1[C@@]21CO1

nearest known ligand 0.80

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PGR P06401 9/20 0.80
AR P10275 9/20 0.80
LMNA P02545 2/20 0.80
NR3C1 P04150 2/20 0.80
ABCC4 O15439 1/20 0.80
ABCB11 O95342 1/20 0.80
CHRM2 P08172 1/20 0.80
HTR2A P28223 1/20 0.80
HTR2B P41595 1/20 0.80
CYP19A1 P11511 9/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Drospirenone SCHEMBL13971411 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL153317 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL13460142 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL13355946 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL18717263 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL13015156 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL18077735 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL14227067 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL22171517 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4
Drospirenone SCHEMBL13356035 0.89 PGR (1.00) PGRARLMNANR3C1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080076915-A1 Epoxidation of 17-oxo-15,16-Methylene Steroids with Sulfoxonium Ylides ANTIBIOTICOS S.P.A. (IT) 2008-03-27 US disclosed
US-20080076915-A1 Epoxidation of 17-oxo-15,16-Methylene Steroids with Sulfoxonium Ylides ANTIBIOTICOS S.P.A. (IT) 2008-03-27 US disclosed
EP-1903051-A2 Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides Antibioticos S.p.A. (IT) 2008-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076915-A1 Epoxidation of 17-oxo-15,16-Methylene Steroids with Sulfoxonium Ylides HSD17B7, CYP17A1, SRD5A2 PGR 441/4885AR 189/4885LMNA 1507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.