Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209490 | 0.85 | MEN1 (0.54) | SMN1; SMN2NPC1MAOBRAB9A | |
| SCHEMBL28544613 | 0.85 | MEN1 (0.54) | SMN1; SMN2NPC1MAOBRAB9A | |
| SCHEMBL28548544 | 0.84 | SRD5A2 (0.56) | ERCC5FEN1FFAR1SRD5A2SMN1; SMN2 | |
| SCHEMBL11594843 | 0.81 | AKR1C3 (0.56) | AKR1C3ERCC5FEN1HDAC8ALDH1A1 | |
| SCHEMBL4708458 | 0.80 | ERCC5 (0.65) | AKR1C3ERCC5FEN1HDAC8FFAR1 | |
| SCHEMBL10266416 | 0.79 | AKR1C3 (0.61) | AKR1C3ERCC5FEN1HDAC8ALDH1A1 | |
| SCHEMBL11639201 | 0.78 | ERCC5 (0.62) | AKR1C3ERCC5FEN1HDAC8FFAR1 | |
| SCHEMBL163962 | 0.78 | MAOA (0.50) | HDAC8MAOB | |
| SCHEMBL11361846 | 0.78 | AKR1C3 (0.51) | AKR1C3ERCC5FEN1HDAC8FFAR1 | |
| SCHEMBL38664634 | 0.77 | KMO (0.48) | ERCC5FEN1HDAC8NR4A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511751-B1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS ANTIVIRAL AGENTS | NEOGENESIS PHARMACEUTICALS INC (US) | 2008-03-19 | — | — | EP | disclosed |