Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2149382 | 0.81 | KDM4E (0.46) | MCL1MAOBNFE2L2KDM4EMEN1 | |
| SCHEMBL27647189 | 0.81 | KDM4E (0.46) | MCL1MAOBNFE2L2KDM4EMEN1 | |
| SCHEMBL30578183 | 0.81 | KDM4E (0.46) | MCL1MAOBNFE2L2KDM4EMEN1 | |
| SCHEMBL14257702 | 0.77 | NFE2L2 (0.40) | MAOBNFE2L2KDM4EMEN1KMT2A | |
| SCHEMBL5388851 | 0.73 | CA1 (0.50) | MAOBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5388848 | 0.73 | CA1 (0.50) | MAOBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19443779 | 0.72 | NFE2L2 (0.43) | NFE2L2RELA | |
| SCHEMBL13176644 | 0.71 | NFE2L2 (0.41) | NFE2L2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL13887136 | 0.68 | NFE2L2 (0.41) | MAOBNFE2L2 | |
| SCHEMBL15919101 | 0.66 | ABCB1 (0.36) | KDM4EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625129-B1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2008-03-05 | — | — | EP | disclosed |