Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578183 | 1.00 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27647189 | 1.00 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14930494 | 0.84 | PTGS2 (0.54) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL149581 | 0.83 | MAOB (0.59) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29900779 | 0.83 | MAOB (0.59) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL149579 | 0.83 | MAOB (0.59) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14257595 | 0.81 | MCL1 (0.38) | KDM4EMEN1KMT2AMAPTMCL1 | |
| SCHEMBL26969013 | 0.81 | ALDH1A1 (0.45) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL15195165 | 0.81 | NFE2L2 (0.54) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5388848 | 0.80 | CA1 (0.50) | KDM4EALDH1A1MAPTMAOBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874436-A | Preparation method of letromycin intermediate | 济宁学院 | 2023-10-13 | — | — | CN | claimed |
| US-RE49698-E1 | Substituted dihydroquinazolines | AIC246 AG & CO. KG (DE) | 2023-10-17 | — | — | US | disclosed |
| US-RE49698-E1 | Substituted dihydroquinazolines | AIC246 AG & CO. KG (DE) | 2023-10-17 | — | — | US | disclosed |
| CN-116874436-A | Preparation method of letromycin intermediate | 济宁学院 | 2023-10-13 | — | — | CN | disclosed |
| CN-116874436-A | Preparation method of letromycin intermediate | 济宁学院 | 2023-10-13 | — | — | CN | disclosed |
| EP-1622880-B3 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |
| EP-1622880-B3 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |
| US-RE46791-E1 | Substituted dihydroquinazolines | AICURIS ANTI-INFECTIVE CURES GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-RE46791-E1 | Substituted dihydroquinazolines | AICURIS ANTI-INFECTIVE CURES GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-9890128-B2 | Process for making substituted quinazoline compounds | MERCK SHARP & DOHME CORP. (US) | 2018-02-13 | — | — | US | disclosed |
| EP-1622880-B1 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1622880-B1 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1685123-A2 | SUBSTITUTED DIHYDROQUINAZOLINES II | Bayer HealthCare AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| EP-1625129-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| EP-1622880-A1 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | Bayer HealthCare AG (DE) | 2006-02-08 | — | — | EP | disclosed |
| EP-1562913-A1 | SUBSTITUTED QUINAZOLINES AS ANTIVIRAL AGENTS, ESPECIALLY AGAINST CYTOMEGALOVIRUSES | Bayer HealthCare AG (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2005047278-A2 | SUBSTITUTED DIHYDROQUINAZOLINES II | BAYER HEALTHCARE AG (DE) | 2005-05-26 | — | — | WO | disclosed |
| WO-2004099212-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004096778-A1 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004041790-A1 | SUBSTITUTED QUINAZOLINES AS ANTIVIRAL AGENTS, ESPECIALLY AGAINST CYTOMEGALOVIRUSES | BAYER HEALTHCARE AG (DE) | 2004-05-21 | — | — | WO | disclosed |