Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821171 | 0.80 | CHRNB2 (0.32) | POLB | |
| SCHEMBL3398592 | 0.80 | CHRNB2 (0.32) | POLB | |
| SCHEMBL2745077 | 0.80 | CHRNB2 (0.32) | POLB | |
| SCHEMBL16494829 | 0.78 | — | — | |
| SCHEMBL18701757 | 0.70 | POLB (0.34) | NR1H2POLB | |
| SCHEMBL6106105 | 0.68 | HSD11B1 (0.33) | — | |
| SCHEMBL6106104 | 0.68 | HSD11B1 (0.33) | — | |
| SCHEMBL6106107 | 0.68 | HSD11B1 (0.33) | — | |
| SCHEMBL6108057 | 0.68 | HSD11B1 (0.33) | — | |
| SCHEMBL6108063 | 0.68 | HSD11B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205589-B1 | C-MET PROTEIN KINASE INHIBITORS | VERTEX PHARMA (US) | 2011-03-23 | — | — | EP | disclosed |