Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA1 | P00915 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170514 | 0.81 | — | — | |
| SCHEMBL24923006 | 0.78 | KDM4E (0.37) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL14601546 | 0.78 | KDM4E (0.37) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL21765847 | 0.78 | KDM4E (0.67) | KDM4EMAPK1HIF1ACA2CA1 | |
| SCHEMBL14981894 | 0.78 | KDM4E (0.67) | KDM4EMAPK1HIF1ACA2CA1 | |
| SCHEMBL10131957 | 0.77 | CA1 (0.38) | CA2CA1ALDH1A1 | |
| SCHEMBL13219609 | 0.77 | KDM4E (0.40) | KDM4EMAPK1HIF1ACA2TSHR | |
| SCHEMBL15698313 | 0.77 | CA1 (0.42) | CA2CA1 | |
| SCHEMBL11887087 | 0.77 | MEN1 (0.50) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL13311543 | 0.76 | CA1 (0.46) | KDM4ECA2CA1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080063701-A1 | Vector | IV VEC LIMITED (GB) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080063701-A1 | Vector | LPCAT1, HDLBP, AGO2 | KDM4E 1447/4885MAPK1 4447/4885HIF1A 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.