Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19509410 | 0.83 | KDM4E (0.39) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL31758443 | 0.83 | KDM4E (0.39) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL12661037 | 0.80 | KDM4E (0.40) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL6754730 | 0.79 | — | — | |
| SCHEMBL14258484 | 0.78 | KDM4E (0.39) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL20960431 | 0.78 | MCL1 (0.43) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL468799 | 0.78 | CTH (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL24198636 | 0.78 | MCL1 (0.43) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL468870 | 0.78 | CTH (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL3623995 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006084-A1 | ANTI-DLL3 ANTIBODY AND PREPARATION METHOD THEREFOR, DRUG CONJUGATE AND APPLICATION THEREOF | 上海复旦张江生物医药股份有限公司 | 2023-02-02 | — | — | WO | disclosed |