Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425599 | 0.87 | PPARD (0.44) | PPARDPPARASMN1; SMN2 | |
| SCHEMBL1425790 | 0.86 | PPARD (0.41) | PPARDPPARA | |
| SCHEMBL12811501 | 0.86 | PPARD (0.43) | PPARDPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1425518 | 0.85 | PPARD (0.41) | PPARDPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1425586 | 0.85 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL12811832 | 0.84 | PPARD (0.44) | PPARDPPARARAB9A | |
| SCHEMBL1426308 | 0.84 | PTGER1 (0.45) | — | |
| SCHEMBL19471103 | 0.83 | PPARD (0.39) | PPARDPPARANPC1RAB9A | |
| SCHEMBL16711678 | 0.83 | PPARD (0.52) | PPARDPPARACHEK2MAOB | |
| SCHEMBL19285699 | 0.79 | KDM1A (0.50) | PARP10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492414-B2 | Antibacterial agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-07-23 | — | — | US | disclosed |
| US-8492414-B2 | Antibacterial agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-07-23 | — | — | US | disclosed |
| EP-2200991-B1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-03-23 | — | — | EP | disclosed |
| US-20100273837-A1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD. (GB) | 2010-10-28 | — | — | US | disclosed |
| US-20100273837-A1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD. (GB) | 2010-10-28 | — | — | US | disclosed |
| EP-2200991-A1 | ANTIBACTERIAL AGENTS | Biota Europe Ltd (GB) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009037485-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273837-A1 | ANTIBACTERIAL AGENTS | SQOR, SCO2, CYCS | PPARD 3071/4885PPARA 2596/4885PARP10 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.