Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11174500 | 0.99 | PNMT (0.50) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7796977 | 0.90 | ADORA1 (0.52) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL1174225 | 0.90 | PNMT (0.65) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27136939 | 0.89 | ADORA1 (0.53) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL3304064 | 0.84 | PNMT (0.55) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL20329146 | 0.84 | KDM4E (0.62) | TDP1KDM4EL3MBTL1ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL29721315 | 0.82 | PNMT (0.55) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11173037 | 0.82 | PNMT (0.55) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11173311 | 0.80 | L3MBTL1 (0.50) | TDP1KDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL16794021 | 0.79 | TDP1 (0.49) | PNMTTDP1KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205589-B1 | C-MET PROTEIN KINASE INHIBITORS | VERTEX PHARMA (US) | 2011-03-23 | — | — | EP | disclosed |
| US-4414225-A | Azepine derivatives and their anti-thrombotic compositions and methods | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-11-08 | — | — | US | disclosed |