Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | SRC | P12931 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14259641 | 0.94 | TDP1 (0.80) | HSD17B10TDP1TP53ALOX15SRC | |
| SCHEMBL7870113 | 0.93 | TDP1 (0.82) | HSD17B10TDP1TP53ALOX15SRC | |
| SCHEMBL7627853 | 0.87 | HSD17B10 (0.80) | HSD17B10TDP1TP53ALOX15SRC | |
| Chicoric Acid SCHEMBL30995918 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC | |
| Chicoric Acid SCHEMBL21176639 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC | |
| Chicoric Acid SCHEMBL961606 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC | |
| Chicoric Acid SCHEMBL963407 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC | |
| Cichoric Acid SCHEMBL29349701 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC | |
| Chicoric Acid SCHEMBL730803 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC | |
| Cichoric Acid SCHEMBL29385936 | 0.84 | HSD17B10 (1.00) | HSD17B10TDP1TP53ALOX15SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | HSD17B10 1111/4885TDP1 135/4885TP53 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.