Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | SRC | P12931 | 2/20 | 0.70 |
| ▸ | APP | P05067 | 8/20 | 0.63 |
| ▸ | TTR | P02766 | 4/20 | 0.63 |
| ▸ | MMP1 | P03956 | 3/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | MMP12 | P39900 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14259643 | 0.93 | HSD17B10 (0.71) | TDP1HSD17B10ALOX15TP53SRC | |
| Cichoric Acid SCHEMBL29385936 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL21176639 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL30518333 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Cichoric Acid SCHEMBL29349701 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL730803 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL30995918 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL963407 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL961606 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL13772650 | 0.91 | HSD17B10 (1.00) | TDP1HSD17B10ALOX15TP53SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306443-B1 | HARVESTING AN ECHINACEA PLANT; SEPARATING THE ECHINACEA PLANT INTO FRAGMENTS; PLACING THE FRAGMENTS IN A CONTAINER PROVIDING SEMI-AEROBIC CONDITIONS; STORING TO INCREASE CONCENTRATION OF CICHORIC ACID AND TETRAENE ALKYLAMIDES | AMWAY CORPORATION | 2001-10-23 | — | — | US | disclosed |