Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | SRC | P12931 | 2/20 | 0.84 |
| ▸ | APP | P05067 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | TTR | P02766 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | MMP1 | P03956 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | APEX1 | P27695 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | LCK | P06239 | 2/20 | 0.65 |
| ▸ | FYN | P06241 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chicoric Acid SCHEMBL13772650 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL30518333 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL964775 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Cichoric Acid SCHEMBL29349701 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL30995918 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL730803 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Cichoric Acid SCHEMBL29385936 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL961606 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Chicoric Acid SCHEMBL21176639 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC | |
| Cichoric Acid SCHEMBL15532218 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1ALOX15TP53SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026902-A1 | Methods and compositions for the treatment or prevention of human immunodeficiency virus and related conditions using cyclooxygenase-2 selective inhibitors and antiviral agents | PHARMACIA CORPORATION | 2005-02-03 | — | — | US | claimed |
| US-8404746-B2 | Anti-diabetes composition containing chicoric acid and/or one of the metabolites thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-26 | — | — | US | disclosed |
| US-20110015140-A1 | ANTI-DIABETES COMPOSITION CONTAINING CHICORIC ACID AND/OR ONE OF THE METABOLITES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-01-20 | — | — | US | disclosed |
| EP-1671535-A1 | Methods for altering levels of phenolic compounds in plant cells | Stiftung Caesar Center of Advanced European Studies and Research (DE) | 2006-06-21 | — | — | EP | disclosed |
| EP-1671534-A1 | Methods for altering levels of phenolic compounds in plant cells | Stiftung Caesar Center of Advanced European Studies and Research (DE) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015140-A1 | ANTI-DIABETES COMPOSITION CONTAINING CHICORIC ACID AND/OR ONE OF THE METABOLITES THEREOF | IAPP, GPR119, HMGCR | HSD17B10 319/4885TDP1 2354/4885ALOX15 2782/4885 |
| US-20050026902-A1 | Methods and compositions for the treatment or prevention of human immunodeficiency virus and related conditions using cyclooxygenase-2 selective inhibitors and antiviral agents | PTGS2, PTGS1, PTGES2 | HSD17B10 314/4885TDP1 1351/4885ALOX15 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.