Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.77 |
| ▸ | PIM1 | P11309 | 3/20 | 0.77 |
| ▸ | CD38 | P28907 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | RECQL | P46063 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.67 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | APEX1 | P27695 | 3/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29575209 | 0.89 | AMY1A (0.77) | AMY1APIM1CD38MEN1KMT2A | |
| SCHEMBL12557418 | 0.89 | AMY1A (0.77) | AMY1APIM1CD38MEN1KMT2A | |
| Quercetagetin SCHEMBL29690479 | 0.87 | AMY1A (1.00) | AMY1APIM1CD38MEN1KMT2A | |
| Quercetagetin SCHEMBL29608135 | 0.87 | AMY1A (1.00) | AMY1APIM1CD38MEN1KMT2A | |
| Quercetagetin SCHEMBL554527 | 0.87 | AMY1A (1.00) | AMY1APIM1CD38MEN1KMT2A | |
| Quercetagetin SCHEMBL7647221 | 0.85 | AMY1A (0.89) | AMY1APIM1CD38MEN1KMT2A | |
| Quercetagetin SCHEMBL28164757 | 0.84 | AMY1A (0.87) | AMY1APIM1CD38MEN1KMT2A | |
| SCHEMBL9909444 | 0.83 | MEN1 (0.75) | AMY1APIM1CD38MEN1KMT2A | |
| SCHEMBL12590257 | 0.83 | MEN1 (0.67) | AMY1APIM1CD38MEN1KMT2A | |
| SCHEMBL31022147 | 0.83 | AMY1A (0.81) | AMY1APIM1CD38MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | AMY1A 4572/4885PIM1 147/4885CD38 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.