SCHEMBL9909444

SCHEMBL9909444

Cc1cc(O)c2c(=O)c(O)c(-c3ccc(O)c(O)c3)oc2c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.75
KMT2A Q03164 11/20 0.75
KDM4E B2RXH2 9/20 0.75
HSD17B10 Q99714 8/20 0.75
MAPT P10636 8/20 0.75
CYP3A4 P08684 7/20 0.75
RECQL P46063 7/20 0.75
ALOX15 P16050 7/20 0.75
CYP1A2 P05177 6/20 0.75
CYP2C9 P11712 6/20 0.75
XDH P47989 6/20 0.75
TP53 P04637 5/20 0.75
IPMK Q8NFU5 5/20 0.75
IP6K2 Q9UHH9 5/20 0.75
APP P05067 5/20 0.75
CYP1A1 P04798 5/20 0.75
CYP1B1 Q16678 5/20 0.75
SLCO2B1 O94956 5/20 0.75
ALDH1A1 P00352 5/20 0.75
HPGD P15428 5/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23919099 0.89 MEN1 (0.65) MEN1KMT2AKDM4EHSD17B10MAPT
SCHEMBL14254533 0.88 MEN1 (0.58) MEN1KMT2AKDM4EHSD17B10MAPT
SCHEMBL14769773 0.87 MEN1 (0.76) MEN1KMT2AKDM4EHSD17B10MAPT
SCHEMBL12305080 0.87 MEN1 (0.73) MEN1KMT2AKDM4EHSD17B10MAPT
Quercetin SCHEMBL27746111 0.86 MEN1 (0.94) MEN1KMT2AKDM4EHSD17B10MAPT
Quercetin SCHEMBL31507620 0.86 MEN1 (1.00) MEN1KMT2AKDM4EHSD17B10MAPT
Quercetin SCHEMBL17629824 0.86 MEN1 (1.00) MEN1KMT2AKDM4EHSD17B10MAPT
Quercetin SCHEMBL118425 0.86 MEN1 (1.00) MEN1KMT2AKDM4EHSD17B10MAPT
Quercetin SCHEMBL29723041 0.86 MEN1 (1.00) MEN1KMT2AKDM4EHSD17B10MAPT
Quercetin SCHEMBL19723 0.86 MEN1 (1.00) MEN1KMT2AKDM4EHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022065914-A1 ANTICOCCIDIAL COMPOSITION COMPRISING GINKGO LEAVES AND USE THEREOF 씨제이제일제당 (주) 2022-03-31 WO disclosed
US-20180100166-A1 Compositions and Methods for Enhancing Bioenergetic Status in Female Germ Cells PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-04-12 US disclosed
US-9845482-B2 Compositions and methods for enhancing bioenergetic status in female germ cells THE GENERAL HOSPITAL CORPORATION (US) 2017-12-19 US disclosed
US-9757407-B2 Treatment of viral infections by modulation of host cell metabolic pathways THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2017-09-12 US disclosed
US-20160346309-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS UNIV PRINCETON (US) 2016-12-01 US disclosed
US-20150139949-A1 ANTI-VIRAL COMBINATION THERAPY KOYUNCU EMRE (US) 2015-05-21 US disclosed
US-9029413-B2 Treatment of viral infections by modulation of host cell metabolic pathways THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-05-12 US disclosed
US-20140221319-A1 Small Molecule CD38 Inhibitors and Methods of Using Same MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2014-08-07 US disclosed
US-20130065850-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2013-03-14 US disclosed
US-20130059384-A1 COMPOSITIONS AND METHODS FOR ENHANCING BIOENERGETIC STATUS IN FEMALE GERM CELLS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-03-07 US disclosed
EP-2460810-A1 NOVEL FLAVANONE DERIVATIVE National University Corporation Okayama University (JP) 2012-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221319-A1 Small Molecule CD38 Inhibitors and Methods of Using Same CD38, CD22, CD2 MEN1 2938/4885KMT2A 1089/4885KDM4E 1900/4885
US-20180100166-A1 Compositions and Methods for Enhancing Bioenergetic Status in Female Germ Cells PCK2, GSR, TFAM MEN1 4369/4885KMT2A 2889/4885KDM4E 2420/4885
US-20160346309-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS GOT2, MAVS, ME3 MEN1 4221/4885KMT2A 3171/4885KDM4E 2299/4885
US-20130059384-A1 COMPOSITIONS AND METHODS FOR ENHANCING BIOENERGETIC STATUS IN FEMALE GERM CELLS PCK2, GSR, TFAM MEN1 4369/4885KMT2A 2889/4885KDM4E 2420/4885
US-20130065850-A1 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS GOT2, MAVS, ME3 MEN1 4221/4885KMT2A 3171/4885KDM4E 2299/4885
US-20150139949-A1 ANTI-VIRAL COMBINATION THERAPY HAVCR2, MAVS, ZC3HAV1 MEN1 4738/4885KMT2A 3077/4885KDM4E 2656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.