Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312485 | 0.89 | ACP1 (0.70) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1085411 | 0.87 | ACP1 (0.87) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1085090 | 0.86 | ACP1 (0.84) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL14259846 | 0.83 | TLR9 (0.68) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL3460750 | 0.80 | ACP1 (0.74) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1084058 | 0.80 | CYP1A2 (0.65) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1085510 | 0.77 | ACP1 (0.70) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1085597 | 0.76 | ACP1 (0.87) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1085329 | 0.76 | ACP1 (0.69) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL3972057 | 0.75 | MAPK1 (0.71) | ACP1MAPK1TSHRALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030455-A2 | SMALL MOLECULE INHIBITORS OF TOLL-LIKE RECEPTOR 9 | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-03-13 | — | — | WO | disclosed |