Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884430 | 0.89 | CYP19A1 (0.46) | ALDH1A1TDP1TSHRCYP19A1CYP3A4 | |
| SCHEMBL4200907 | 0.85 | SMN1; SMN2 (0.52) | MCHR1ALDH1A1TDP1CYP19A1CYP3A4 | |
| SCHEMBL1811361 | 0.85 | CHRNB2 (0.59) | ALDH1A1TDP1TSHRCYP19A1CYP3A4 | |
| SCHEMBL22381241 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP19A1CYP3A4 | |
| SCHEMBL6927122 | 0.83 | CYP19A1 (0.48) | TDP1TSHRCYP19A1CHRNB2CHRNA4 | |
| SCHEMBL3859288 | 0.82 | KCNH2 (0.52) | ALDH1A1TDP1TSHRCYP19A1CYP3A4 | |
| SCHEMBL6924138 | 0.80 | CYP19A1 (0.43) | TDP1TSHRCYP19A1CHRNB2CHRNA4 | |
| SCHEMBL12121522 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRCYP19A1CYP3A4 | |
| SCHEMBL5866590 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRCYP3A4S1PR4 | |
| SCHEMBL1646321 | 0.79 | MAPT (0.52) | ALDH1A1TDP1TSHRCYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058515-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058515-A1 | Chemical Compounds | SGK1, SGK2, SGK3 | MCHR1 4225/4885ALDH1A1 2338/4885TDP1 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.