Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CTSG | P08311 | 7/20 | 0.50 |
| ▸ | KLK7 | P49862 | 7/20 | 0.50 |
| ▸ | KLK14 | Q9P0G3 | 7/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915806 | 0.80 | HSD17B10 (0.67) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL8068689 | 0.77 | HSD17B10 (1.00) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL913374 | 0.76 | ALDH1A1 (1.00) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL914097 | 0.76 | ALDH1A1 (0.81) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL13701234 | 0.76 | ALDH1A1 (0.72) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL913449 | 0.76 | ALDH1A1 (1.00) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL8070379 | 0.73 | KDM4E (0.75) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL914239 | 0.73 | KDM4E (0.67) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL8059761 | 0.73 | MAPK1 (0.72) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL13700976 | 0.72 | ALDH1A1 (0.66) | HSD17B10MAPK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339057-B2 | Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and carboxylic acid in the presence of a sulfonyl chloride and pyridine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-7339057-B2 | Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and carboxylic acid in the presence of a sulfonyl chloride and pyridine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-7276601-B2 | Method and preparing fused oxazinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-7276601-B2 | Method and preparing fused oxazinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |