Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14254541 | 0.97 | CYP1B1 (0.55) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| SCHEMBL14263859 | 0.96 | MAOB (0.60) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| SCHEMBL14254555 | 0.89 | MAOB (0.52) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| SCHEMBL1421382 | 0.80 | CYP1B1 (0.86) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| SCHEMBL29845342 | 0.80 | CYP1B1 (0.86) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| Methane SCHEMBL27890494 | 0.79 | CYP1B1 (0.84) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| SCHEMBL27907057 | 0.79 | CYP1B1 (0.84) | CYP1B1MAOBCYP19A1MAPTCYP1A1 | |
| SCHEMBL14254536 | 0.78 | KDM4E (0.63) | MAPTCYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL11306051 | 0.77 | PTGS1 (0.57) | CYP1B1MAOBMAPTCYP1A1CYP1A2 | |
| SCHEMBL6096166 | 0.77 | CYP1B1 (0.72) | CYP1B1MAOBCYP19A1MAPTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345090-B2 | Galenical formulation | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-03-18 | — | — | US | disclosed |