Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264177 | 0.80 | TDP1 (0.44) | MAPTALDH1A1CYP2A6KCNA3KCNA5 | |
| SCHEMBL13799209 | 0.76 | ALDH1A1 (0.45) | MAPTALDH1A1CYP2A6MCL1MAOA | |
| SCHEMBL29434953 | 0.76 | MAPT (0.43) | MAPTALDH1A1CYP2A6KCNA3KCNA5 | |
| SCHEMBL999018 | 0.76 | MAPT (0.43) | MAPTALDH1A1CYP2A6KCNA3KCNA5 | |
| SCHEMBL8750110 | 0.76 | CYP2A6 (0.45) | MAPTALDH1A1CYP2A6PGRMCL1 | |
| SCHEMBL14278036 | 0.74 | ALDH1A1 (0.37) | MAPTALDH1A1KCNA3KCNA5PGR | |
| SCHEMBL14264184 | 0.74 | CYP19A1 (0.34) | MAPTALDH1A1KCNA3KCNA5CYP19A1 | |
| SCHEMBL9149685 | 0.72 | MAPT (0.58) | MAPTALDH1A1CYP2A6GAAMEN1 | |
| SCHEMBL13799205 | 0.72 | KMT2A (0.40) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13799210 | 0.72 | KCNA3 (0.33) | MAPTALDH1A1KCNA3KCNA5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076778-A1 | METHODS FOR DESIGNING PARP INHIBITORS AND USES THEREOF | BIPAR SCIENCES, INC. (US) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076778-A1 | METHODS FOR DESIGNING PARP INHIBITORS AND USES THEREOF | PARP3, PARP1, PARP15 | MAPT 3488/4885ALDH1A1 1787/4885CYP2A6 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.