Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578170 | 0.79 | ALDH1A1 (0.55) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL14264177 | 0.76 | TDP1 (0.44) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL13799209 | 0.76 | ALDH1A1 (0.45) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL999018 | 0.76 | MAPT (0.43) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29434953 | 0.76 | MAPT (0.43) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL663238 | 0.74 | TDP1 (0.57) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL8039855 | 0.74 | MEN1 (1.00) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL20125060 | 0.74 | MAPT (0.66) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL28007963 | 0.73 | ALDH1A1 (0.47) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL10565737 | 0.73 | MAOA (0.55) | MAPTMEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609211-A4 | ADENOSINE DIPHOSPHORIBOSE POLYMERASE BINDING NITROSO AROMATIC COMPOUNDS USEFUL AS ANTI-TUMOR AND ANTI-RETROVIRAL AGENTS. | OCTAMER INC (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0609211-A1 | ADENOSINE DIPHOSPHORIBOSE POLYMERASE BINDING NITROSO AROMATIC COMPOUNDS USEFUL AS ANTI-TUMOR AND ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1994-08-10 | — | — | EP | disclosed |