Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.58 |
| ▸ | CTSK | P43235 | 10/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 4/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096778 | 1.00 | CTSS (0.58) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL28969878 | 0.87 | CTSS (0.57) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL1311509 | 0.84 | ITGB3 (0.67) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL1062486 | 0.84 | ITGB3 (0.67) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL5065823 | 0.84 | ITGB3 (0.67) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL13252087 | 0.84 | ABCB1 (0.58) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL30336908 | 0.83 | ABCB1 (0.56) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL25607238 | 0.83 | ABCB1 (0.46) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL13933239 | 0.83 | ABCB1 (0.57) | CTSSCTSKABCB1CTSBCTSL | |
| SCHEMBL13252035 | 0.83 | ABCB1 (0.57) | CTSSCTSKABCB1CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070308-A1 | Portous Article For Delivering Chemical Substances | LIFECYCLE PHARMA A/S (DK) | 2008-03-20 | — | — | US | disclosed |
| US-20080070308-A1 | Portous Article For Delivering Chemical Substances | LIFECYCLE PHARMA A/S (DK) | 2008-03-20 | — | — | US | disclosed |