Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 14/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSMG3 | Q9BT73 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264242 | 0.85 | IMPDH2 (0.33) | IMPDH2ALDH1A1PSMG3 | |
| SCHEMBL14264241 | 0.84 | IMPDH2 (0.32) | IMPDH2ALDH1A1 | |
| SCHEMBL11558269 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2ALOX5POLB | |
| SCHEMBL13363738 | 0.71 | IMPDH2 (0.40) | IMPDH2KDM4ESMN1; SMN2POLB | |
| SCHEMBL4473151 | 0.71 | CYP3A4 (0.38) | IMPDH2KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL25330017 | 0.70 | IMPDH2 (0.38) | IMPDH2IMPDH1ALOX5 | |
| SCHEMBL24596055 | 0.70 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2ABCB11POLB | |
| SCHEMBL23280986 | 0.70 | ALDH1A1 (0.41) | IMPDH2IMPDH1KDM4EALDH1A1 | |
| SCHEMBL21602868 | 0.69 | IMPDH2 (0.41) | IMPDH2IMPDH1ALOX5 | |
| SCHEMBL32689518 | 0.69 | IMPDH2 (0.41) | IMPDH2IMPDH1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348113-B2 | Electrophotographic photoconductor comprising a polycarbonate resin having a dihydroxy diphenyl ether unit | RICOH COMPANY, LTD. (JP) | 2008-03-25 | — | — | US | disclosed |