Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.65 |
| ▸ | ECE1 | P42892 | 2/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CASP9 | P55211 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827209 | 0.95 | FOLH1 (0.65) | MMEECE1FOLH1CASP1CASP3 | |
| SCHEMBL910232 | 0.95 | FOLH1 (0.70) | MMEECE1FOLH1CASP1NAALAD2 | |
| SCHEMBL910423 | 0.95 | FOLH1 (0.70) | MMEECE1FOLH1CASP1NAALAD2 | |
| Benzene SCHEMBL28226069 | 0.95 | FOLH1 (0.70) | MMEECE1FOLH1CASP1NAALAD2 | |
| SCHEMBL910233 | 0.95 | FOLH1 (0.70) | MMEECE1FOLH1CASP1NAALAD2 | |
| SCHEMBL13957718 | 0.94 | MME (0.64) | MMEECE1FOLH1CASP1CASP3 | |
| SCHEMBL10397579 | 0.94 | MME (0.67) | MMEECE1FOLH1CTSLNAALAD2 | |
| SCHEMBL1426719 | 0.94 | MME (0.64) | MMEECE1FOLH1CASP1CASP3 | |
| SCHEMBL13884435 | 0.94 | MME (0.64) | MMEECE1FOLH1CASP1CASP3 | |
| SCHEMBL30902878 | 0.92 | MME (0.56) | MMEECE1FOLH1CASP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509643-A1 | Anti-cancer compounds | BTG INTERNATIONAL LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |