Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 4/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1348375 | 0.75 | SLC6A3 (0.49) | CNR1CNR2 | |
| SCHEMBL1350846 | 0.72 | NPSR1 (0.36) | CNR1CNR2 | |
| SCHEMBL8667654 | 0.71 | EEF2K (0.49) | EEF2KFFAR1RECQLSMN1; SMN2 | |
| SCHEMBL5721003 | 0.70 | LMNA (0.50) | EEF2KSMN1; SMN2 | |
| SCHEMBL5721001 | 0.70 | LMNA (0.50) | EEF2KSMN1; SMN2 | |
| SCHEMBL19420118 | 0.70 | EEF2K (0.48) | EEF2KCTSAFFAR1RECQLSMN1; SMN2 | |
| SCHEMBL17755077 | 0.70 | FFAR1 (0.56) | EEF2KFFAR1SMN1; SMN2 | |
| SCHEMBL19420103 | 0.70 | EEF2K (0.48) | EEF2KCTSAFFAR1RECQLSMN1; SMN2 | |
| SCHEMBL3865104 | 0.68 | EEF2K (0.46) | EEF2KCACNA1GCTSAFFAR1RECQL | |
| SCHEMBL21851962 | 0.68 | LMNA (0.47) | EEF2KFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300423-A1 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009156072-A1 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-12-30 | — | — | WO | disclosed |