SCHEMBL1426751

SCHEMBL1426751

C=CC(=O)N(C(=O)O)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18527055 0.87 TSHR (0.39) LMNATSHRALDH1A1
SCHEMBL18677617 0.81 ALDH1A1 (0.39) TSHRALDH1A1
SCHEMBL27600789 0.80 TSHR (0.32) LMNATSHR
SCHEMBL6249962 0.76 TP53 (0.39)
SCHEMBL5666057 0.76 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL20998428 0.76 TSHR (0.35) TSHR
SCHEMBL5698301 0.75 TSHR (0.37) LMNATSHRALDH1A1
SCHEMBL1817729 0.74
SCHEMBL1817732 0.74
SCHEMBL21911261 0.74 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231858-B1 PATTERNED CELL SHEETS AND A METHOD FOR PRODUCTION OF THE SAME KONINKL PHILIPS NV (NL) 2015-11-04 EP claimed
US-9675417-B2 Safe ablation KONINKLIJKE PHILIPS N.V. (NL) 2017-06-13 US disclosed
EP-2522679-B1 PHENYLBORONIC ACID MONOMER AND PHENYLBORONIC ACID POLYMER NAT INST FOR MATERIALS SCIENCE (JP) 2016-07-13 EP disclosed
US-9267109-B2 Patterned cell sheets and a method for production of the same KONINKLIJKE PHILIPS N.V. (NL) 2016-02-23 US disclosed
EP-2320823-B1 SAFE ABLATION KONINKL PHILIPS NV (NL) 2016-01-27 EP disclosed
EP-2231858-B1 PATTERNED CELL SHEETS AND A METHOD FOR PRODUCTION OF THE SAME KONINKL PHILIPS NV (NL) 2015-11-04 EP disclosed
US-8382339-B2 Light output device KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2013-02-26 US disclosed
US-8323221-B2 Tissue temperature indicating element for ultrasound therapy KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2012-12-04 US disclosed
EP-2522679-A1 PHENYLBORONIC ACID MONOMER AND PHENYLBORONIC ACID POLYMER National Institute for Materials Science (JP) 2012-11-14 EP disclosed
US-20120283403-A1 Phenylboronic Acid Monomer and Phenylboronic Acid Polymer NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2012-11-08 US disclosed
WO-2008135899-A1 BIO-RECOGNITION SENSOR WITH ACTUATION DEVICE KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-11-13 WO disclosed
WO-2008132651-A1 MICROMIXER AND/OR MICROREACTOR WITH ACTIVE FLOW CONTROLLING MEANS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-11-06 WO disclosed
WO-2008117223-A1 A MICRO-FLUIDIC DEVICE COMPRISING AN INTERNAL ACTUATION ELEMENT KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-10-02 WO disclosed
EP-1972376-A1 A micro-fluidic device based upon active matrix principles Koninklijke Philips Electronics N.V. (NL) 2008-09-24 EP disclosed
EP-1966599-A1 MAGNETOCHEMICAL SENSOR Koninklijke Philips Electronics N.V. (NL) 2008-09-10 EP disclosed
WO-2008090501-A1 PROCESS FOR TREATING CULTURED CELLS KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-07-31 WO disclosed
WO-2008068678-A1 BIOTECHNOLOGICAL DEVICE INCLUDING AN ACTUATION MEANS FOR CHANGING THE MOBILITY OF PRESELECTED BIOMOLECULES KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-06-12 WO disclosed
WO-2008068676-A1 BIOTECHNOLOGICAL DEVICE INCLUDING A STRUCTURED HYDROGEL PERMEATION LAYER KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-06-12 WO disclosed
WO-2007135651-A1 A BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-11-29 WO disclosed
WO-2007072243-A1 MAGNETOCHEMICAL SENSOR KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283403-A1 Phenylboronic Acid Monomer and Phenylboronic Acid Polymer MAPK13, PAH, MAP3K13 LMNA 865/4885TSHR 1658/4885ALDH1A1 2148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.