Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398261 | 0.86 | TSHR (0.36) | TSHRALDH1A1FGFR4 | |
| SCHEMBL18527055 | 0.81 | TSHR (0.39) | TSHRALDH1A1LMNAFGFR4 | |
| SCHEMBL1041496 | 0.79 | TSHR (0.37) | TSHRALDH1A1LMNATP53FGFR4 | |
| SCHEMBL17598953 | 0.77 | TSHR (0.36) | TSHRALDH1A1LMNAFGFR4 | |
| SCHEMBL646634 | 0.77 | — | — | |
| SCHEMBL28078636 | 0.77 | TSHR (0.36) | TSHRALDH1A1LMNA | |
| SCHEMBL1426751 | 0.75 | LMNA (0.35) | TSHRALDH1A1LMNA | |
| SCHEMBL18677617 | 0.75 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL3280368 | 0.74 | — | — | |
| SCHEMBL28218381 | 0.74 | TSHR (0.37) | TSHRALDH1A1LMNAFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1295113-B1 | NON-THERMOSENSITIVE MEDIUM FOR ANALYSING SPECIES INSIDE A CHANNEL | INST CURIE (FR) | 2006-07-26 | — | — | EP | claimed |
| EP-1360215-A2 | TREATMENT SOLUTION MINIMISING ADSORPTION AND/OR ELECROOSMOSIS PHENOMENA | Institut Curie (FR) | 2003-11-12 | — | — | EP | claimed |
| EP-1295113-A2 | NON-THERMOSENSITIVE MEDIUM FOR ANALYSING SPECIES INSIDE A CHANNEL | Institut Curie (FR) | 2003-03-26 | — | — | EP | claimed |
| WO-2002000746-A2 | TREATMENT SOLUTION MINIMISING ADSORPTION AND/OR ELECROOSMOSIS PHENOMENA | INSTITUT CURIE (FR) | 2002-01-03 | — | — | WO | claimed |
| WO-2002001218-A2 | NON-THERMOSENSITIVE MEDIUM FOR ANALYSING SPECIES INSIDE A CHANNEL | INSTITUT CURIE (FR) | 2002-01-03 | — | — | WO | claimed |
| EP-1295113-B1 | NON-THERMOSENSITIVE MEDIUM FOR ANALYSING SPECIES INSIDE A CHANNEL | INST CURIE (FR) | 2006-07-26 | — | — | EP | disclosed |
| EP-1360215-A2 | TREATMENT SOLUTION MINIMISING ADSORPTION AND/OR ELECROOSMOSIS PHENOMENA | Institut Curie (FR) | 2003-11-12 | — | — | EP | disclosed |
| EP-1295113-A2 | NON-THERMOSENSITIVE MEDIUM FOR ANALYSING SPECIES INSIDE A CHANNEL | Institut Curie (FR) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002001218-A2 | NON-THERMOSENSITIVE MEDIUM FOR ANALYSING SPECIES INSIDE A CHANNEL | INSTITUT CURIE (FR) | 2002-01-03 | — | — | WO | disclosed |
| WO-2002000746-A2 | TREATMENT SOLUTION MINIMISING ADSORPTION AND/OR ELECROOSMOSIS PHENOMENA | INSTITUT CURIE (FR) | 2002-01-03 | — | — | WO | disclosed |