Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268578 | 0.87 | HTT (0.36) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268573 | 0.82 | THRB (0.38) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14607774 | 0.80 | THRB (0.35) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL12387272 | 0.79 | TDP1 (0.41) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268572 | 0.75 | THRB (0.42) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268571 | 0.75 | MAPT (0.39) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268595 | 0.74 | THRB (0.34) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268575 | 0.74 | APP (0.37) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268598 | 0.71 | SNCA (0.38) | THRBTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL14268596 | 0.68 | TSHR (0.33) | THRBTDP1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329289-B2 | Use of triarylmethane derivatives as direct dyes in a dye composition, composition and implementation process | L'Oréal, S.A. (FR) | 2008-02-12 | — | — | US | disclosed |