Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387272 | 0.92 | TDP1 (0.41) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268571 | 0.88 | MAPT (0.39) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL17615865 | 0.85 | KDM4E (0.34) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268575 | 0.85 | APP (0.37) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268572 | 0.85 | THRB (0.42) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268578 | 0.83 | HTT (0.36) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268574 | 0.83 | THRB (0.39) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14607774 | 0.83 | THRB (0.35) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268570 | 0.82 | THRB (0.33) | THRBTDP1MEN1RECQLKMT2A | |
| SCHEMBL14268595 | 0.81 | THRB (0.34) | THRBTDP1MEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329289-B2 | Use of triarylmethane derivatives as direct dyes in a dye composition, composition and implementation process | L'Oréal, S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| EP-1623701-B1 | Use of triarylmethane derivatives in colourant compositions, compositions and their methods of use. | OREAL (FR) | 2007-02-14 | — | — | EP | disclosed |