SCHEMBL14269381

SCHEMBL14269381

CN1C(=O)C(=C/C=C2\OCCN2C)C(=O)N(C)C1=O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.37
▸ HPGD P15428 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.34
▸ MAPT P10636 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ RECQL P46063 1/20 0.34
▸ KDM4C Q9H3R0 1/20 0.34
▸ XDH P47989 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ APP P05067 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058860 1.00 KMT2A (0.37) KMT2AHPGDSMN1; SMN2ALDH1A1MAPT
SCHEMBL2058863 1.00 KMT2A (0.37) KMT2AHPGDSMN1; SMN2ALDH1A1MAPT
SCHEMBL19240007 0.85 KMT2A (0.37) KMT2AHPGDSMN1; SMN2ALDH1A1MAPT
SCHEMBL17897726 0.81 KMT2A (0.34) KMT2AHPGDSMN1; SMN2ALDH1A1MAPT
SCHEMBL18590878 0.80 KMT2A (0.33) KMT2AHPGDSMN1; SMN2ALDH1A1MAPT
SCHEMBL19240019 0.74 ALDH1A1 (0.46) KMT2AALDH1A1MAPTAPPPOLB
SCHEMBL19239988 0.73 MAPT (0.55) KMT2ASMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL13683551 0.71 — —
SCHEMBL17897728 0.71 XDH (0.35) KMT2AHPGDSMN1; SMN2ALDH1A1MAPT
SCHEMBL19239998 0.71 MEN1 (0.58) KMT2ASMN1; SMN2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7326517-B2 Planographic printing plate material and preparing process of planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-02-05 — — US disclosed
US-7326517-B2 Planographic printing plate material and preparing process of planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-02-05 — — US disclosed
US-7316892-B2 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2008-01-08 — — US disclosed
US-7316892-B2 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2008-01-08 — — US disclosed
US-7192690-B2 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 — — US disclosed
US-7192690-B2 Process of preparing planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 — — US disclosed
EP-1586460-B1 Photosensitive composition, planographic printing plate material, and preparing process of planographic printing plate KONICA MINOLTA MED & GRAPHIC (JP) 2007-03-07 — — EP disclosed
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