Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14272812 | 0.86 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1MAPTSMN1; SMN2TP53 | |
| SCHEMBL14272930 | 0.83 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTSMN1; SMN2TP53 | |
| SCHEMBL14272931 | 0.82 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTSMN1; SMN2TP53 | |
| SCHEMBL14047625 | 0.78 | SCD (0.57) | ALDH1A1MAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL14047400 | 0.78 | SCD (0.57) | ALDH1A1MAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL14047581 | 0.72 | ALDH1A1 (0.45) | ALDH1A1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14047421 | 0.72 | SCD (0.59) | ALDH1A1SMN1; SMN2TP53TSHR | |
| SCHEMBL3046713 | 0.71 | SCD (0.63) | — | |
| SCHEMBL14047409 | 0.71 | SCD (0.47) | MAPTSMN1; SMN2TP53LMNAKDM4E | |
| SCHEMBL14047404 | 0.71 | SCD (0.47) | MAPTSMN1; SMN2TP53LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036715-A1 | HETEROCYCLIC ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-03-27 | — | — | WO | disclosed |