Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14272857 | 0.92 | L3MBTL1 (0.42) | L3MBTL1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL13542617 | 0.88 | GPR119 (0.41) | L3MBTL1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL7624926 | 0.85 | PDK2 (0.45) | MEN1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL14272830 | 0.74 | PDK2 (0.39) | L3MBTL1GPR119PDK2ACACBATM | |
| SCHEMBL8316463 | 0.73 | MEN1 (0.42) | MEN1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL31693911 | 0.73 | PDK2 (0.40) | L3MBTL1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6588671 | 0.73 | PDK2 (0.47) | ALDH1A1GPR119PDK2ATMALOX15 | |
| SCHEMBL31693830 | 0.72 | PDK2 (0.41) | ALDH1A1LMNASMN1; SMN2NPSR1GPR119 | |
| SCHEMBL14272825 | 0.71 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2ASMN1; SMN2GPR119 | |
| SCHEMBL3723723 | 0.70 | ATM (0.44) | L3MBTL1MEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329673-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329673-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-02-12 | — | — | US | disclosed |