Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273423 | 0.85 | P2RY12 (0.58) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL1639032 | 0.80 | P2RY12 (0.51) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL14273426 | 0.79 | KMT2A (0.41) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL27756391 | 0.78 | P2RY12 (0.42) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL27756531 | 0.77 | P2RY12 (0.43) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL1639033 | 0.76 | P2RY12 (0.48) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL27777254 | 0.75 | P2RY12 (0.41) | P2RY12SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL1639567 | 0.73 | P2RY12 (0.49) | P2RY12SMN1; SMN2LMNAKDM4ERXFP1 | |
| SCHEMBL1640891 | 0.72 | P2RY12 (0.57) | P2RY12SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL12768944 | 0.72 | MAPK1 (0.50) | P2RY12SMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036843-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |