Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273352 | 0.79 | P2RY12 (0.44) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL14273423 | 0.79 | P2RY12 (0.58) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL1640093 | 0.78 | P2RY12 (0.44) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL13635285 | 0.71 | P2RY12 (0.63) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL13635628 | 0.67 | HTR3A (0.41) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL13634875 | 0.67 | P2RY12 (0.49) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL1640891 | 0.65 | P2RY12 (0.57) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL1640127 | 0.65 | P2RY12 (0.53) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL1639033 | 0.65 | P2RY12 (0.48) | KMT2AGAATP53MAPTALDH1A1 | |
| SCHEMBL1639567 | 0.65 | P2RY12 (0.49) | KMT2AGAATP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036843-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |