Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 4/20 | 0.50 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11947174 | 0.92 | ALDH1A1 (0.60) | CYP17A1NAMPTALDH1A1L3MBTL1ABCC9 | |
| SCHEMBL18570243 | 0.92 | CYP17A1 (0.61) | CYP17A1NAMPTALDH1A1BCL2BECN1 | |
| SCHEMBL22548863 | 0.87 | CYP17A1 (0.57) | CYP17A1NAMPTL3MBTL1CD274PSMB8 | |
| SCHEMBL3360413 | 0.86 | CYP17A1 (0.63) | CYP17A1NAMPTBCL2BECN1CD274 | |
| SCHEMBL20865536 | 0.86 | CYP17A1 (0.68) | CYP17A1NAMPTL3MBTL1CD274PSMB8 | |
| SCHEMBL8770870 | 0.83 | NAMPT (0.67) | CYP17A1NAMPTCD274MEN1NPC1 | |
| SCHEMBL775002 | 0.82 | NAMPT (0.56) | CYP17A1NAMPTALDH1A1PSMB8PDK1 | |
| SCHEMBL14263398 | 0.82 | CYP17A1 (0.50) | CYP17A1NAMPTBCL2BECN1CD274 | |
| SCHEMBL14263314 | 0.82 | S1PR4 (0.60) | CYP17A1NAMPTALDH1A1L3MBTL1CD274 | |
| SCHEMBL17526122 | 0.82 | NAMPT (0.73) | NAMPTALDH1A1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-03-13 | — | — | US | disclosed |
| US-7241812-B2 | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | S1PR1, S1PR2, S1PR3 | CYP17A1 2209/4885NAMPT 1134/4885ALDH1A1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.