Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 5/20 | 0.37 |
| ▸ | NECTIN4 | Q96NY8 | 2/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | KCNMB4 | Q86W47 | 1/20 | 0.36 |
| ▸ | RXFP4 | Q8TDU9 | 1/20 | 0.36 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.36 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274877 | 0.98 | CTSL (0.57) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274875 | 0.97 | CTSL (0.57) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274867 | 0.97 | CTSL (0.61) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274884 | 0.97 | CTSL (0.53) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274850 | 0.97 | CTSL (0.60) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274725 | 0.96 | CTSL (0.59) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274694 | 0.96 | CTSL (0.60) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274724 | 0.96 | CTSL (0.63) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274866 | 0.96 | CTSL (0.55) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274843 | 0.96 | CTSL (0.55) | CTSLDRD1PTGS1PDE4AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249074-A1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2014-09-04 | — | — | US | disclosed |
| US-20080051326-A1 | Antiinfective Lipopeptides | CUBIST PHARMACEUTICALS, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051326-A1 | Antiinfective Lipopeptides | VIP, NGLY1, PREP | CTSL 49/4885DRD1 3359/4885PTGS1 765/4885 |
| US-20140249074-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | CTSL 868/4885DRD1 3591/4885PTGS1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.