Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 19/20 | 0.77 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14276729 | 0.87 | SLC9A1 (1.00) | SLC9A1SLC9A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL14276728 | 0.86 | SLC9A1 (1.00) | SLC9A1SLC9A2 | |
| SCHEMBL14276734 | 0.84 | SLC9A1 (1.00) | SLC9A1SLC9A2 | |
| SCHEMBL14276748 | 0.84 | SLC9A1 (0.86) | SLC9A1SLC9A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL14276875 | 0.83 | SLC9A1 (0.66) | SLC9A1MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14276836 | 0.83 | SLC9A1 (0.69) | SLC9A1SLC9A2 | |
| SCHEMBL14276742 | 0.82 | SLC9A1 (1.00) | SLC9A1SLC9A2 | |
| SCHEMBL14276736 | 0.82 | SLC9A1 (0.78) | SLC9A1SLC9A2 | |
| SCHEMBL14276811 | 0.82 | SLC9A1 (0.78) | SLC9A1SLC9A2 | |
| SCHEMBL14276731 | 0.81 | SLC9A1 (1.00) | SLC9A1MEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |