Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 19/20 | 0.72 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14276755 | 0.92 | SLC9A1 (0.73) | SLC9A1SLC9A2 | |
| SCHEMBL14276863 | 0.88 | SLC9A1 (0.66) | SLC9A1SLC9A2KDM4E | |
| SCHEMBL14276866 | 0.87 | SLC9A1 (0.61) | SLC9A1SLC9A2 | |
| SCHEMBL14276862 | 0.86 | SLC9A1 (0.68) | SLC9A1SLC9A2KDM4E | |
| SCHEMBL14276869 | 0.86 | SLC9A1 (0.67) | SLC9A1SLC9A2 | |
| SCHEMBL14276867 | 0.84 | SLC9A1 (0.54) | SLC9A1SLC9A2 | |
| SCHEMBL14276839 | 0.84 | SLC9A1 (1.00) | SLC9A1SLC9A2 | |
| SCHEMBL30772134 | 0.84 | SLC9A1 (1.00) | SLC9A1SLC9A2 | |
| SCHEMBL16588925 | 0.83 | SLC9A1 (0.76) | SLC9A1SLC9A2 | |
| SCHEMBL14276870 | 0.83 | SLC9A1 (0.52) | SLC9A1SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |